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Omar Skalli Selected Research

desmuslin (synemin)

1/2016Synemin: Molecular Features and the Use of Proximity Ligation Assay to Study Its Interactions.
3/2015Roles and potential clinical applications of intermediate filament proteins in brain tumors.
1/2014Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease.
10/2013Astrocytoma grade IV (glioblastoma multiforme) displays 3 subtypes with unique expression profiles of intermediate filament proteins.
4/2012Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.
9/2008Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton.
4/2007Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.
9/2006Synemin expression is widespread in liver fibrosis and is induced in proliferating and malignant biliary epithelial cells.
4/2005Intermediate filament protein synemin is present in human reactive and malignant astrocytes and associates with ruffled membranes in astrocytoma cells.

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Omar Skalli Research Topics

Disease

9Neoplasms (Cancer)
12/2021 - 08/2002
7Astrocytoma (Pilocytic Astrocytoma)
01/2016 - 08/2002
5Glioblastoma (Glioblastoma Multiforme)
01/2017 - 08/2002
2Wounds and Injuries (Trauma)
01/2016 - 11/2010
2Breast Neoplasms (Breast Cancer)
01/2016 - 08/2002
2Gliosis
01/2014 - 11/2010
2Carcinoma (Carcinomatosis)
09/2008 - 09/2006
1Colitis
12/2021
1Carcinogenesis
12/2021
1Dysbiosis
08/2021
1Cysts
08/2021
1Chloracne
08/2021
1Inflammation (Inflammations)
08/2021
1Body Weight (Weight, Body)
08/2021
1Brain Neoplasms (Brain Tumor)
03/2015
1Glioma (Gliomas)
03/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2014
1Alexander Disease (Alexander's Disease)
01/2014
1Bullous Pemphigoid (Pemphigoid)
02/2013
1Retinal Detachment (Retinal Detachments)
11/2010
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
04/2009
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
04/2009
1Hepatocellular Carcinoma (Hepatoma)
09/2006
1Cholangiocarcinoma
09/2006
1Hepatitis
09/2006
1Liver Diseases (Liver Disease)
09/2006
1Liver Cirrhosis (Hepatic Cirrhosis)
09/2006
1Fatty Liver
09/2006

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
01/2017 - 08/2002
9desmuslin (synemin)IBA
01/2016 - 04/2005
4VimentinIBA
03/2015 - 04/2007
4NestinIBA
03/2015 - 04/2007
4Glial Fibrillary Acidic ProteinIBA
01/2014 - 04/2007
3Protein Isoforms (Isoforms)IBA
01/2016 - 08/2002
3ActininIBA
04/2010 - 04/2005
2Biological ProductsIBA
01/2018 - 10/2013
2Intermediate Filament ProteinsIBA
03/2015 - 10/2013
1LipidsIBA
12/2021
1Ethanol (Ethyl Alcohol)IBA
12/2021
1AzoxymethaneIBA
12/2021
1CarcinogensIBA
12/2021
1DNA (Deoxyribonucleic Acid)IBA
12/2021
1RNA (Ribonucleic Acid)IBA
12/2021
1Dextran SulfateIBA
12/2021
1LigandsIBA
08/2021
1Polychlorinated Dibenzodioxins (TCDD)IBA
08/2021
1PolymersIBA
01/2020
1Temozolomide (Temodar)FDA LinkGeneric
01/2017
1CateninsIBA
01/2017
1Biomarkers (Surrogate Marker)IBA
01/2017
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
03/2015
1Crystallins (Crystallin)IBA
01/2014
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2014
1AntigensIBA
02/2013
1IntegrinsIBA
02/2013
1Retinaldehyde (Retinal)IBA
11/2010
1Peptide Hydrolases (Proteases)FDA Link
06/2009
1UbiquitinIBA
04/2009
1VinculinIBA
09/2008
1PlectinIBA
08/2002
1Complementary DNA (cDNA)IBA
08/2002
1Hyaluronic Acid (Hyaluronan)IBA
08/2002
1EpitopesIBA
08/2002
1Hyaluronan ReceptorsIBA
08/2002
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2002
1Monoclonal AntibodiesIBA
08/2002

Therapy/Procedure

1Therapeutics
03/2015